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Ajinomoto BioPharma Services

Senior Partner

Ajinomoto Bio-Pharma Services offers comprehensive capabilities for small molecule APIs and biologics production, from process development and cGMP manufacturing to aseptic fill finish, including cytotoxics. As a global CDMO, we provide the adaptive solutions, responsive service, trusted partnership and peace of mind you’ve come to rely on.  Ajinomoto Bio-Pharma Services is establishing itself as a premier, US-based provider for high-containment bioconjugate manufacturing, as well as fill and finish services for both Highly Potent Active Pharmaceutical Intermediates (HPAPI) and Antibody Drug Conjugates (ADC).

www.ajibio-pharma.com

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Femtogenix

Senior Partner

Femtogenix was founded in 2015 to discover and develop next generation DNA-interactive payload molecules for use in antibody-drug conjugates. Our payloads are designed through a development platform combining proprietary computational chemistry techniques, and founder know-how gained from a combined 50+ years of experience in DNA-targeted drug discovery and development.

Our drug discovery platform allows us to design molecules capable of binding reversibly and/or irreversibly to DNA, in a sequence-interactive manner, leading to exquisite cytotoxicity toward tumour cells. When attached to antibodies or other targeting moieties, these potent cytototoxic agents can be delivered directly to tumours with minimal general systemic toxicities for patients.

Our management and scientific teams consist of highly experienced scientists with the expertise and drive to translate our novel platform into tangible results for cancer patients.

www.femtogenix.com

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Merck

Senior Partner

Merck is the leading Life Science company, providing solutions as a strategic partner to help advance the promise of life-saving therapies. We have the largest offering of products for formulations, actives, and biotechnology processes. Our joint ADC offering includes a full range of integrated contract manufacturing services for drug development and manufacturing that spans conjugation, mAbs, linkers, and payloads. To fit your ADC manufacturing needs, we offer a comprehensive processing portfolio from cell culture media to buffers, salts, and stabilizers and from chromatography to TFF equipment, including single-use templates.

https://www.merckmillipore.com/DE/en/20170213_16015

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Abtis

Partner

AbTis is the bio-technology company which specializes in antibody-drug Conjugation technology and Solubilization of drugs through Micelle format with its own proprietary patents.

Our pipelines are designed to enhance the safety and efficacy of the current antibody drug conjugates by applying AbTis linker to the mAbs.Our technology is applicable to the native antibodies, commercial antibodies or novel antibodies under development as it requires no mutation or engineering to antibody itself.

AbTis is one of the leading bio-conjugation companies. We seek to create positive economic impact and long-term value, improved quality of life for the patients worldwide. AbTis was founded in 2016 by Professor Sang Jeon Chung, our Chairman and Chief Executive Officer, in 2017 it was seed funded $ 0.5 million and 2018 June, we secured $ 4.5 million private placement from 3 venture capital firms which are Stonebridge capital partners, K2 Investment and JX partners.

abtis.co.kr

 

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Abzena

Partner

We are Abzena – Built to deliver. Created to care.

Abzena is a global development and manufacturing partner that provides integrated discovery, development and manufacturing services for biologics and bioconjugates to the biopharmaceutical industry. We help our partners to take their innovative discoveries from early-phase development through to commercial manufacture by tailoring our approach from concept to clinic. Our vision is to accelerate the development of biologic treatments and bioconjugates so that suffering of patients is prevented, and lifespan improved.

www.abzena.com

 

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ALMAC DISCOVERY

Partner

Almac Discovery is an innovative biotech company operating within and supported by the Almac Group of companies. We are led by an experienced team (ex-Pharma and Biotech), with a track record in delivering successful clinical programmes.

We utilise our capabilities and expertise to discover and develop NCEs and Novel Protein Therapeutics through to the pre-clinical candidate/IND-ready stage, after which we seek to collaborate with partners to continue their development.

www.almacgroup.com/discovery/

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AMRI

Partner

AMRI, a global contract research and manufacturing organization, partners with the pharmaceutical and biotechnology industries to improve patient outcomes and quality of life. With locations in North America, Europe and Asia, AMRI’s team combines scientific expertise and market-leading technology to provide a complete suite of solutions in Discovery, Development, Analytical and Solid State Services, API Manufacturing and Drug Product. For more information about AMRI, visit

https://www.amriglobal.com

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BSP Pharmaceuticals

Partner

BSP Pharmaceuticals is a Contract Development and Manufacturing Organization fully dedicated to antineoplastic  drugs, designed to handle the complexity of biopharmaceutical products and offering customized services to support its client from development to commercial manufacturing of injectables and oral formulations. BSP Pharmaceuticals is focused on innovative therapies such as Proteosome Inhibitors, Antibody Drug Conjugates (ADCs) , Liposomal formulations, handling the major platforms of ADC compounds currently in clinical and commercial phase.

www.bsppharmaceuticals.com

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CARBOGEN AMCIS

Partner

CARBOGEN AMCIS combines world-class chemistry skills to provide seamless drug development and commercialization services for pharmaceutical and biotechnology companies. Through our customized offering we provide an array of integrated process research and manufacturing services to support the fast supply of complex Antibody Drug Conjugates (ADCs). Our infrastructure is fully cGMP compliant and includes a clean room dedicated to ADCs in Switzerland and a formulation site with lyophilization capabilities in France.

www.carbogen-amcis.com

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Catalent Biologics

Partner

Catalent Biologics provides advanced technologies and solutions for protein and gene therapy development, manufacturing and clinical supply. With technology platforms including GPEx® cell line engineering, SMARTag® bioconjugation and AAV viral vector expression combined with comprehensive analytical services and fill/finish supply, Catalent Biologics is your premier partner for clinical and commercial success.

www.biologics.catalent.com

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CFM OSKAR TROPITZSCH GMBH

Partner

We supply the keys to new therapies

Leading biotech companies rely on Cfm Oskar Tropitzsch GmbH for the sustainable procurement of toxins as payloads for ADCs, linker-drug conjugates, peptide linkers for ADCs including substances with a novel / special mode of action.

Because of the close cooperation with ADC experts worldwide, we can offer the following services: conjugation partners, contract manufacturing specialists, experts for security assessments and most important active marketing of potential payload candidates.

Young startups in particular benefit from our global network.

www.cfmot.de

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Heraeus

Partner

We are a reliable supplier of HPAPIs for the pharmaceutical industry specialized in fighting cancer.

Besides our platinum-based and organic HPAPIs, we have an extensive knowledge in manufacturing and purification of different payload and linker classes in the ADC field.

As CDMO we support our customers in the exclusive synthesis of cytotoxic compounds from research stage to registration and market launch.

Heraeus, headquartered in Hanau, Germany, is a leading international family-owned company formed in 1851.

www.heraeus.com

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ILC Dover

Partner

ILC Dover is a world-leader in the innovative design and production of engineered flexible protective solutions. Based in Frederica, Delaware, we serve the pharmaceutical industry with single-use flexible powder solutions that facilitate safe and reliable performance and productivity in the lab. CMOs and CDMOs choose our solutions for powder transfers and containment over rigid stainless-steel systems, for the significant advantages they bring to chemical synthesis of HPAPI and OSD processing for final drug products.

www.ilcdover.com

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Novasep

Partner

Novasep has been a leading contract service provider in the ADC arena for more than 10 years and provides unique services for the development, clinical supply and commercial manufacture of antibody-drug conjugates including the payload, the linker and the monoclonal antibody.

Our commitment to ADCs is underlined by the recent €11M investment in a stand-alone bioconjugation unit at our Le Mans site in France. The site has more than 30 years of experience in synthesis & purification of cytotoxics using industrial chromatography.

www.novasep.com

 

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Piramal

Partner

Piramal Pharma Solutions is a contract development and manufacturing organization (CDMO), offering end-to-end development and manufacturing solutions across the drug life cycle. We serve our clients through a globally integrated network of facilities in North America, Europe and Asia. This enables us to offer a comprehensive range of services including Drug Discovery Solutions, Process & Pharmaceutical Development services, Clinical Trial Supplies, Commercial supply of APIs and Finished dosage forms. We also offer specialized services like development and manufacture of Highly Potent APIs and Antibody Drug Conjugation. Our capability as an integrated service provider & experience with various technologies enables us to serve Innovator and Generic companies worldwide.

www.piramalpharmasolutions.com

 

 

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Proveo

Partner

Formed in 2015, PROVEO is now a Division of Cerbios- Pharma SA focused on complete supply chain solution for Antibody Drug Conjugates (ADCs).
Thanks to the partnership with AGC Biologics and Oncotec, PROVEO offer best-in-class solutions for the integrated development and cGMP manufacturing of recombinant proteins (incl mAbs), cytotoxic drug-linker payload, conjugation, aseptic fill and lyophilization. Strengths of the three PROVEO partners secure a seamless and low risk ADC supply chain for clinical and commercial projects.

www.proveoadc.com

 

 

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Safebridge

Partner

SafeBridge Consultants, Inc. is the premier resource for high-level safety, health and environmental support to the pharmaceutical and biotechnology industry.  Comprised of industry leaders in toxicology, analytical chemistry and industrial hygiene. SafeBridge has developed the “brand name” in the pharmaceutical industry as a leader in the field of advanced worker protection programs for potent drug handling and risk assessment for product protection. SafeBridge has locations in Mountain View, California, New York City and London, England.

www.safebridge.com

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Sartorius

Partner

The Sartorius Group is a leading international partner of the biopharmaceutical industry and the research sector. We are helping biotech scientists and engineers across the entire globe to develop and manufacture medications from the first idea to production. So more people will have access to better medicine.

www.sartorius.com/en