Contrasting Discovery & Preclinical Head‑to‑Head Comparison of Two ADCs

• Pharmaron’s fully integrated ADC platform enables comprehensive discovery and preclinical characterisation
• Direct comparison of SG and Dato‑DXd with pH‑sensitive and protease‑specific linkers, respectively
• Assessment of how linker‑driven payload release influences efficacy, in vitro and in vivo bystander effects, dosing, and safety
• Complete physicochemical, structural, in vitro, in vivo, DMPK, and toxicology assessment

Speakers:

Hua Yang

Chief Scientific Officer

Pharmaron