Hua Yang
Seminars
Tuesday 9th March 2027
Contrasting Discovery & Preclinical Head-to-Head Comparison of Two ADCs
2:15 pm
- Comparing SG and Dato-DXd with pH-sensitive and protease-specific linkers, respectively
- Assessing how linker-driven payload release influences efficacy, in vitro and in vivo bystander effects, dosing, and safety
- Completing physicochemical, structural, in vitro, in vivo, DMPK, and toxicology assessment
