Discovery & Development of Click-to Release ADCs With Enhanced Therapeutic Potential
11:15 am - Wednesday 10th March 2027
- Using the learnings from first in class clinical stage click-cleavable ADC TGW101 against TAG72 in next-generation designs to further expand the ADC target universe into the non internalizing target space
- Highlighting how the Click-to-Release linker system affords a highly differentiated safety and efficacy profile across several payload classes
- Discussing protein design considerations and functional characterisation of our discovery phase ADCs