Raffaella Rossin

Seminars

Wednesday 10th March 2027
Discovery & Development of Click-to- Release ADCs With Enhanced Therapeutic Potential
11:15 am
  • Using the learnings from first in class clinical stage click-cleavable ADC TGW101 against TAG72 in next-generation designs to further expand the ADC target universe into the noninternalizing target space
  • Highlighting how the Click-to-Release linker system affords a highly differentiated safety and efficacy profile across several payload classes
  • Discussing protein design considerations and functional characterisation of our discovery-phase ADCs