Scott Lesley
President & Chief Scientific Officer InduPro
Scott Lesley is InduPro’s President & Chief Scientific Officer leading all platform and drug discovery functions at the Company.
Prior to joining InduPro, Scott was Vice President of Discovery Biologics at Merck and was responsible for a broad preclinical pipeline of molecules across all therapeutic areas within Merck. This included diverse modalities such as multifunctional antibodies and engineered proteins, ADCs, oncolytic viruses and cell therapies.
Prior to his role at Merck, Scott was at Novartis. He joined the Genomics Institute of the Novartis Research Foundation (GNF) at its inception. There, he established research and technology platforms in biotherapeutics, protein engineering, protein structure and function, and high-throughput technologies. In his role as the Executive Director of Biotherapeutics and Biotechnology he oversaw scientists and engineers responsible for biotherapeutics discovery and optimization, structural biology, HTS, functional genomics, automation and engineering.
Scott also maintained a faculty appointment at The Scripps Research Institute from 2005-2016 and led an independent research lab as Co-PI of the Joint Center for Structural Genomics (JCSG) studying protein structure and function with an emphasis on host/microbe interactions. The JCSG was responsible for over 1600 novel protein structures.
Prior to joining GNF, he was a Sr. Research Scientist at Promega Corporation and has had postdoctoral positions at the University of California, Berkeley, and the University of Wisconsin, Madison. Scott received his Ph.D. in Molecular Biology from the University of Wisconsin and a B.S. in Microbiology from the University of Illinois. He has over 200 publications to date and has contributed to novel therapeutic targets, therapeutic modalities, small molecule and biotherapeutic clinical candidates and registered drugs, as well as developing platform technologies in HTS and other automation for drug discovery.
Seminars
- Target definition through proximity
- Creating dual targeting TAPA ADCs
- Selectivity and efficacy over single targets