Jesús Fuentes Antrás
Seminars
Monday 8th March 2027
Tracking Immunity After the Payload: Longitudinal Biomarkers for Rational ADC Immunotherapy Combinations
12:00 pm
- Distinguishing clinical activity from true immune synergy, examining how to separate an additive response from a genuine interaction so developers can make combination decisions earlier and with more confidence
- Exploring how payload-driven cell death releases antigen, drives presentation and triggers T-cell expansion, and which of these steps can be reliably measured in patients
- Assessing how biomarker data can guide the choice of partner, and the sequencing that follows