Chaoran Jing
Principal Scientist Pfizer
I graduated from Columbia University in 2013 with PhD in chemistry, and started working in the biotech industry. I was Sr Scientist at CytomX Therapeutics 2019 – 2022, then Principal Scientist at Seagen/Pfizer since 2022. At Pfizer, I work in the conjugation team to support ADC programs from early discovery to candidate stages.
Seminars
Wednesday 10th March 2027
Aggregation Analysis for Novel, Challenging ADC Conjugates
12:15 pm
- Exploration of analytical strategies for aggregation assessment in next-generation ADCs that fall outside the capabilities of standard platform SEC methods
- Integration of SEC, SEC-MALS, and DLS to overcome characterisation challenges associated with highly hydrophobic, aggregation-prone conjugates
- Case study showing how orthogonal aggregation data accelerated candidate down-selection and informed key discovery-stage decisions on drug loading and conjugation strategy
