Panel Discussion: Dual Payload & Novel ADCs – Balancing Enhanced Efficacy Against Overlapping Toxicities & Strategies for Effective Translation in Models & in the Clinic
1:30 pm - Monday 8th March 2027
- How can multiple payloads overcome tumour heterogeneity, resistance, and enhance anti-tumour efficacy?
- Discussing the strategies to mitigate overlapping toxicities, optimise therapeutic windows, and balance increased potency with safety profiles through development
- Examining how preclinical models, biomarker strategies, and translational approaches can better predict clinical outcomes and support the successful development of advanced ADC formats in the clinic
