Residual Toxin Removal: Scale & Phase Appropriate Approaches & Challenges

  • Using three model ADCs with variability in  toxin-linker properties to explore residual  toxin removal methods and their applicability  across a set of key toxin classes
  • Assessing challenges in residual toxin  removal change from discovery to  manufacturing
  • Evaluating approaches to improving ADC  quality with residual toxin removal