From Target to Clinic – Development & Manufacturing of the First in Class VARTUMAB ADC

2:02 pm - Tuesday 9th March 2027

  • Oncofetal chondroitin sulfate, an abundant pan-cancer target present on cancer cells and in the tumor stroma
  • Selection of a monovalent scFv–Fc VARTUMAB ADC format, enabling a homogeneous DAR2 construct with deep tumor penetration and potent bystander activity
  • GMP manufacturing and control of VARTUMAB ADC achieving high yield, purity and stability

Speakers:

Senior Director, Bioconjugation & CMC
VAR2 Pharmaceuticals