Considerations for Analytical Characterisation of Antibody- Oligonucleotide Conjugates
2:15 pm - Wednesday 10th March 2027
- Developing analytical tools for antibody-oligonucleotide conjugates and overcoming the challenges for characterisation method development
- Determining the exact oligonucleotideto-antibody ratio (OAR) and similarity to to DAR challenges in ADCs
- Measuring intact AOC and overcoming challenges with structural complexity, charge variants and aggregation