Challenges in XDC Analytical & Functional Characterisation

• XDCs are not a single modality but a family of highly diverse conjugate formats
• The combination of different targeting moieties, linker chemistries, payload classes, and conjugation strategies generates substantial molecular heterogeneity that cannot be captured by traditional biologics characterisation approaches alone
• Sharing case-studies of XDC attributes and development requiring integrated, orthogonal characterisation strategies that combine advanced analytics with functional assays

Speakers:

Alain BECK

Senior Director, Biologics CMC and Developability

Pierre Fabre