Ruud Coumans

Ruud Coumans

Company: Byondis

Job title: Project Leader Antibody-Drug Conjugates

Seminars:

Live Discussion & Question Time 2:30 pm

Read more

day: Track A - Day 2 PM

A Platform for the Generation of Site-Specific Antibody–Drug Conjugates That Allows for Selective Reduction of Engineered Cysteines 2:10 pm

Through use of an in silico screening procedure, optimal sites for conjugating a hydrophobic payload were identified Compared to randomly conjugated ADCs, the site-specific ADCs were less hydrophobic and had better efficacy and exposure in an in vivo xenograft model The site-specific ADCs can be manufactured using a newly discovered selective reducing agent that is…Read more

day: Track A - Day 2 PM

© Copyright 2018 Hanson Wade | Design and site by Event Engine | Hanson Wade Limited is registered in England & Wales, number 06752216.
Registered Office: Suite A, 6 Honduras Street, London EC1Y 0TH.