Piet van der Graaf
Senior Vice President, Head of Quantitative Systems Pharmacology Certara
Piet van der Graaf is Senior Vice President Applied BioSimulation at Certara, Professor of Systems Pharmacology at Leiden University, and Professor of Pediatrics at Cincinnati Children’s Hospital Medical Center. Previously, he was the Director of the Leiden Academic Centre for Drug Research and held leadership positions at Pfizer in Discovery Biology, DMPK and Clinical Pharmacology. He was the founding Editor-in-Chief of CPT: Pharmacometrics & Systems Pharmacology before becoming Editor-in-Chief of Clinical Pharmacology & Therapeutics. Piet received his doctorate training in clinical medicine with Nobel prize laureate Sir James Black at King’s College London. He was awarded the 2024 Gary Neil Prize for Innovation in Drug Development from the American Society of Clinical Pharmacology and Therapeutics (ASCPT) and the 2021 Leadership Award from the International Society of Pharmacometrics (ISoP). Piet is an elected Fellow of the British Pharmacological Society and has published >250 articles in the area of quantitative pharmacology and drug development.
Seminars
- Exploring how model-informed strategies transform ADC development from discovery through translation
- Demonstrating modelling and simulation approaches to optimise ADC design, prioritise high potential candidates, and guide smarter translation
- Understanding how an integrated, end-to-end framework strengthens trial design, reduces uncertainty, and accelerates next-generation ADC development
- Highlighting organ-on-a-chip platforms that deepen mechanistic understanding and improve prediction of human-specific drug behavior
