Philip Moquist

Director, ADC Chemistry Pfizer

Phil Moquist is a director ADC Chemistry at Pfizer. He worked at Seagen for nearly a decade focusing on various aspects of ADC design. His expertise is in payload and linker design with a current focus on discovering novel chemotypes. Prior to Seagen, he received a PhD from Boston University and a BS from UC San Diego.

Seminars

Tuesday 24th February 2026
Auristatin S: Developing an Auristatin Payload with Improved Tolerability & Modified Bystander Activity
11:00 am
  • Rationally designing Auristatin S to improve tolerability of auristatin payloads through the tuning of permeability and bystander activity
  • Explaining how Auristatin S maintains key auristatin properties including strong tubulin binding affinity and induction of immunogenic cell death
  • Exploring Austin S improved preclinical therapeutic window
Philip Moquist Speaker Photo - 16th World ADC London Summit