Philip Moquist
Director, ADC Chemistry Pfizer
Phil Moquist is a director ADC Chemistry at Pfizer. He worked at Seagen for nearly a decade focusing on various aspects of ADC design. His expertise is in payload and linker design with a current focus on discovering novel chemotypes. Prior to Seagen, he received a PhD from Boston University and a BS from UC San Diego.
Seminars
Tuesday 24th February 2026
Auristatin S: Developing an Auristatin Payload with Improved Tolerability & Modified Bystander Activity
11:00 am
- Rationally designing Auristatin S to improve tolerability of auristatin payloads through the tuning of permeability and bystander activity
- Explaining how Auristatin S maintains key auristatin properties including strong tubulin binding affinity and induction of immunogenic cell death
- Exploring Austin S improved preclinical therapeutic window
