A Translational Approach to ADC Evaluation: From In Vitro Organoids to Advanced In Vivo Models
- Exploring the assessment of ADC efficacy through single-mouse in vitro PDXO, MiniPDX, PDX, and clinical MiniPDX models
- Demonstrating how models bridge preclinical findings to clinical indications, offering insights into drug efficacy and resistance
- Highlighting the integration of diverse models to accelerate ADC development and guide decision-making in pharmaceutical R&D