Xiaobin Xu

Xiaobin Xu

Company: Regeneron

Job title: Staff Scientist


Site-Specific Quantitation of Drug Conjugations on Antibody-Drug Conjugates Using a Protease-Assisted Drug Deconjugation & Linker-like Labelling (PADDLL) Method 12:00 pm

Gain insight into the novel proteaseassisted drug deconjugation and linkerlike labelling (PADDLL) method that was developed to quantify the levels of linker payload at specific conjugation sites Understand how this method was successfully applied on two cysteinelinked, protease-cleavable ADCs, and the method demonstrated good linearity and reliability, reaching a limit of quantitation of below 1%…Read more

day: Track D - Day 2

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