Raffaella Faggioni

Raffaella Faggioni

Company: Exelixis

Job title: VP, Clinical & Translational Pharmacology


XB002: Model-Based Dose Selection for a Novel Anti-Tissue Factor ADC With a ZLA Payload for the Treatment of Solid Tumours 11:45 am

Review how efficacy data from Pharmacology tumour models in mice and PK data from monkeys were used to predict XB002 human PK and estimate human efficacious dose Understand how nonclinical safety in cynomolgus monkeys demonstrated adequate safety margins for the range of doses explored in the FTIH study Assess how the PK model was fitted…Read more

day: Track B - Day 1 - AM

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