Graham Cotton

Graham Cotton

Company: Almac Discovery

Job title: Head of Protein Therapeutics

Seminars:

Live Discussion & Question Time 2:30 pm

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day: Track A - Day 1 PM

A Differentiated Next Generation Protein Drug Conjugate for the Treatment of ROR1 Positive Tumours 1:50 pm

Novel ROR1 specific protein drug conjugates (PDCs) have been developed, based on small VNAR targeting domains, that offer potential improvements over conventional ADC approaches. By exploiting a novel cleavable linker payload platform, a pre-clinical candidate has been identified which is highly efficacious in vivo in ROR1+ TNBC and other tumour models where it shows sustained…Read more

day: Track A - Day 1 PM

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