Progress Towards Safe, Curative Treatment of Blood & Immune Diseases: Development of Novel Antibody Conditioning Regimens for Hematopoietic Cell Transplantation

Time: 1:30 pm
day: Track B - Day 2 PM


  • Hematopoietic stem cell transplantation can be used to cure diverse blood and immune diseases
  • Host stem cells compete with donor stem cells for engraftment, but the host stem cells can be selectively depleted with antibodies to enable improved donor stem cell engraftment
  • Understand how antibody-drug-conjugates can be used in this setting as potent conditioning agents for stem cell transplantation